At the moment, there's no cure for a broken heart. Once your heart muscle is damaged by a heart attack, it can never fully recover. But there is hope.
We're funding Dr Tim Chico and his team at the MRC Centre for Developmental and Biomedical Genetics. Here they explain the science behind our Appeal.
We need to spend £50 million to fund groundbreaking research that could begin to literally 'mend broken hearts' in as little as ten years time.
Your support can give hope to hundreds of thousands of people across the UK.